Isotope-Based Method for Detecting Unknown Selenium Compounds

2025.11.20

Research

Selenium-based compounds play vital roles in human and animal health; however, accurately detecting their various forms has long been a challenge. Researchers from Chiba University have developed a new method that uses selenium’s unique isotopic “fingerprints” to identify its compounds with high precision. Using this approach, they discovered previously unknown selenium molecules produced by gut bacteria. This technique could contribute to the fields of biology, helping deepen our understanding of selenium’s functions in the body.

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    Image of an isotope pattern screening technique for the selective detection of
    selenium (Se)-containing compounds using liquid chromatography (LC)-electrospray ionization mass spectrometry.